The author goes into the history of the disease, its complex lifecycle and how it has factored into the course of human history. �`�acܡi�9��XP�mQ�ԏ5�����f�)�I7=�6 ���b*����d�s��d^�m& �� B@ڣ��A���Q,���� r��d�ݘ malaria parasites. It is also because the most effective malaria vector – the mosquito Anopheles gambiae– is the most widespread in Africa and the most difficult to control. Targeting the blood stage The majority of available antimalarials target the blood stage in the parasite lifecycle, since this leads to the clinical symptoms of malaria. �D It is a tropical infectious disease and almost 90 per cent of the cases are from Sub-Saharan Africa. Kept my interest throughout. Print Book & E-Book. Available in PDF, EPUB, Mobi Format. MALARIA POCKET GUIDE FOR CLINICIANS OCTOBER 2010 WHAT IS MALARIA? According to the World Health Organization (WHO) a child dies every 45 seconds as a result of the disease. The drug or drug combination recommended for each specific situation are listed in bold on the first line of each box in the adult and pediatric dosing columns. Malaria is one of the major causes of preventable death in the world today. Malaria prevention is difficult, and no drug is universally effective. Malaria symptoms can develop as early as 7 days after being bitten by an infectious mosquito in a malaria-endemic area and as late as several months or more after exposure. A fascinating and shocking historical exposé, The Malaria Project is the story of America's secret mission to combat malaria during World War II—a campaign modeled after a German project which tested experimental drugs on men gone mad from syphilis. Delay in treating malaria, especially P. falciparum the species of the parasite that is the main cause of the severe forms of the disease may result in Prevention and treatment of malaria is more complex due to the emergence of drug resistance, pesticide resistant mosquito vectors, and large populations of infected people in many areas of the world. Malaria in Mexico; Map 2-19. While I knew some of the facts, the author came up with some intriguing new insights. Malaria is a febrile illness caused by a mosquito-borne protozoan that parasitizes human red blood cells. Symptoms include fever, headache and vomiting. Collection of the University of Hongkong ts 03/07. It affects more than 500 million people worldwide and causes 1 to 2 million deaths every year. The greatest Suspected or confirmed malaria, especially P. falciparum , is a medical emergency requiring urgent intervention, as clinical deterioration can occur rapidly and unpredictably. 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